Método de suplementación de zinc orgánico y respuesta productiva de cerdos en etapa de iniciación en clima cálido

Juan Romo-Valdez, Rubén Barajas-Cruz, Gabriela Silva-Hidalgo, Idalia Enríquez-Verdugo, Héctor Güémez-Gaxiola, Javier Romo-Rubio

Resumen


Con el objetivo de evaluar la respuesta productiva de cerdos en etapa de iniciación bajo condiciones de alta carga de calor ambiental a la suplementación adicional con zinc orgánico, se usaron 816 lechones (21 días de edad y 6.280 ±0.817 kg de peso corporal), nacidos de madres que fueron suplementadas con 0 ó 100 mg Zn/kg de dieta durante la gestación y lactación, bajo un diseño de bloques completos al azar con arreglo factorial 2 x 2 x 2. El experimento se realizó en dos periodos: 1) Mayo-julio y 2) Septiembre-noviembre; cada uno con una duración de 49 días. En cada periodo, 408 lechones fueron agruparon por peso en 3 grupos uniformes, distribuidos en 12 corraletas (6 repeticiones/tratamiento). Los niveles de suplementación adicional probados fueron de 0 y 100 mg Zn/kg de dieta y los tratamientos consistieron en: 1) Madres no suplementadas-lechones no suplementados (Testigo); 2) Madres no suplementadas-lechones suplementados (ZnC); 3) Madres suplementadas-lechones no suplementados (ZnGL) y 4) Madres suplementadas-lechones suplementados (ZnGL + ZnC). Los cerdos se alimentaron con dietas que cubrieron sus requerimientos nutrimentales durante el experimento. El THI promedio fue de 78.19±2.9 durante el periodo de prueba. No existió interacción entre tratamientos sobre las variables evaluadas. El suplementar Zn orgánico durante el periodo de gestación-lactación tendió (P=0.06) a disminuir la mortalidad; sin embargo, el continuar con la suplementación adicional durante la fase de iniciación no ofreció ventaja. No existieron diferencias en las otras variables evaluadas en el grupo suplementado debido al método de suplementación. Se concluye que la suplementación adicional con 100 mg de Zn a partir de Metionina de Zinc durante la fase de gestación-lactación ayuda a disminuir la mortalidad en la etapa de iniciación, en lechones criados en clima cálido.

Palabras clave


Metionina de Zinc; lechones; mortalidad; desempeño productivo

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Referencias


AGGARWAL A, Upadhyay R. 2013. Thermoregulation. In: A. Aggarwal, editor, Heat stress and animal productivity. Springer Press, New Delhi, India. p. 27–42. ISBN: 978-81-322-0879-2

ANSES (French Agency for Food, Environmental and Occupational Health & Safety). 2013. Opinion of the on the use of zinc oxide in the diet of piglets at weaning to reduce the use of antibiotics. ANSES Opinion. Request No. 2012-SA-0067 Available online: http://www.anses.fr/sites/default/files/documents/ALAN2012sa0067Ra.pdf

BAUMGARD LH, Rhoads Jr. RP. 2013. Effects of heat stress on postabsorptive metabolism and energetics. Annual Review of Animal Biosciences. 1:311–337. ISSN: 2165-8102. http://dx.doi.org/10.1146/annurev-animal-031412-103644

BORAH S, Sarmah BC, Chakravarty P, Naskar S, Dutta DJ, Kalita D. 2014. Effect of zinc supplementation on serum biochemicals in grower pig. Journal of Applied Animal Research. 42 (2): 244- 248. ISSN: 0971-2119. http://dx.doi.org/10.1080/09712119.2013.824888

CAINE WR, Metzler-Zebeli BU, McFall M, Miller B, Ward TL, Kirkwood RN, Mosenthin R. 2009. Supplementation of diets for gestating sows with zinc amino acid complex and gastric intubation of suckling pigs with zinc-methionine on mineral status, intestinal morphology and bacterial translocation in lipopolysaccharide-challenged early-weaned pigs. Research in Veterinary Science. ISSN: 0034-5288. 86(3):453–462. http://dx.doi.org/10.1016/j.rvsc.2008.10.005. Epub 2008 Dec 4

CHASAPIS CT, Loutsidou AC, Spiliopoulou CA, Stefanidou ME. 2012. Zinc and human health: an update. Archives of Toxicology. 86(4):521–534. ISSN: 0340-5761. http://dx.doi.org/10.1007/s00204-011-0775-1

DAVIN R, Manzanilla EG, Klasing KC, Perez JF. 2013. Effect of weaning and in-feed high doses of zinc oxide on zinc levels in different body compartments of piglets. Journal of Animal Physiology and Animal Nutrition. 97, (Suppl. s1): 6-12. ISSN:0931-2439. http://dx.doi.org/10.1111/jpn.12046.

DEBSKI B. 2016. Supplementation of pigs diet with zinc and copper as alternative to conventional antimicrobials. Polish Journal of Veterinary Sciences. 19 (4): 917–924. ISSN: 2300-2557. http://dx.doi.org/10.1515/pjvs-2016-0113

EFSA FEEDAP Panel (EFSA Panel on Additives and Products or Substances used in Animal Feed). 2014. Scientific Opinion on the potential reduction of the currently authorised maximum zinc content in complete feed. EFSA Journal. 12(5):3668-3677. ISSN 1831 – 4732. http://dx.doi.org/10.2903/j.efsa.2014.3668

HU CH, Xiao K, Song J and Luan ZS. 2013. Effects of zinc oxide supported on zeolite on growth performance, intestinal microflora and permeability, and cytokines expression of weaned pigs. Animal Feed Science and Technology. 181:65–71. ISSN: 0377-8401. Disponible en: https://www.sciencedirect.com/science/article/pii/S0377840113000539?via%3Dihub

INEU RP, Oliveira CS, Oliveira VA, Moraes-Silva L, da Luz SCA, and Pereira ME. 2013. Antioxidant effect of zinc chloride against ethanol-induced gastrointestinal lesions in rats. Food and Chemical Toxicology. 58:522–529. ISSN:0278-6915. Disponible en: https://ac.els-cdn.com/S0278691513003268/1-s2.0-S0278691513003268-main.pdf?_tid=spdf-ddb64d0c-4bd4-4a3a-9a00-202221d993a4&acdnat=1519702406_629c8214116f88bad65642b760dc3ff1

LAGANA C, Ribeiro AML, Kessler A, Kratz LR, Pinheiro CC. 2007. Effect of the supplementation of vitamins and organic minerals on the performance of broilers under heat stress. Brazilian Journal of Poultry Science. 9(1):39–43. ISSN 1516-635X. http://dx.doi.org/10.1590/S1516-635X2007000100006

LAMBERT GP. 2008. Intestinal barrier dysfunction, endotoxemia, and gastrointestinal symptoms: The ‘canary in the coal mine’ during exercise heat-stress. Medicine and Sport Science. 53:61–73. ISSN, 02545020. http://dx.doi.org/10.1159/000151550

LI Y, Cao Y, Zhou X, Wang F, Shan T, Li Z, Xu W, Li C. 2015. Effects of zinc sulfate pretreatment on heat tolerance of Bama miniature pig under high ambient temperature. Journal of Animal Science. 93(7):3421–3430. ISSN: 0021-8812. https://doi.org/10.2527/jas.2015-8910

MADER TL, Davis MS, Brown-Brandl T. 2006. Environmental factors influencing heat stress in feedlot cattle. Journal of Animal Science. 84:712-719. ISSN: 0021-8812. Disponible en:http://digitalcommons.unl.edu/cgi/viewcontent.cgi?article=1622&context=animalscifacpub

MAHAN DC, Vallet JL. 1997. Vitamin and mineral transfer during fetal development and the early postnatal period in pigs. Journal of Animal Science. 75(10):2731–2738. ISSN: 0021-8812. http://dx.doi.org/10.2527/1997.75102731x

MARET W, Sandstead HH. 2006. Zinc requirements and the risks and benefits of zinc supplementation. Journal of Trace Elements in Medicine and Biology. 20(1):3−18. ISSN, 0946672X. https://doi.org/10.1016/j.jtemb.2006.01.006

MARET W. 2013. Zinc biochemistry: From a single zinc enzyme to a key element of life. Advances in Nutrition. 4(1):82−91. ISSN‎: ‎2161-8313. http://dx.doi.org/10.3945/an.112.003038.

MOLIST F, Hermes RG, Gómez de Segura A, Martín-Orúe SM, Gasa J, Garcia Manzanilla E and Pérez JF, 2011. Effect and interaction between wheat bran and zinc oxide on productive performance and intestinal health in post-weaning piglets. British Journal of Nutrition. 105(11):1592−1600. ISSN: 0007-1145. http://doi.org/10.1017/S0007114510004575

MORALES J, Cordero G, Piñeiro C, Durosoy S. 2012. Zinc oxide at low supplementation level improves productive performance and health status of piglets. Journal of Animal Science. 90 (suppl. 4): 436–438. ISSN: 0021-8812. https://doi.org/10.2527/jas.53833.

NRC. 2012. Nutrient requirements of swine. 11th rev. ed. Natl. Acad. Press, Washington, DC. ISBN: 978-0-309-22427-7, DOI: https://doi.org/10.17226/13298

PAYNE RL, Bidner TD, Fakler TM and LL Southern. 2006. Growth and intestinal morphology of pigs from sows fed two zinc sources during gestation and lactation. Journal of Animal Science. 84:2141-214. ISSN: 0021-8812. https://dx.doi.org/10.2527/jas.2005-627

PEARCE SC, Gabler NK, Ross JW, Escobar J, Patience JF, Rhoads RP, Baumgard LH. 2013b. The effects of heat stress and plane of nutrition on metabolism in growing pigs. Journal of Animal Science. 91(5):2108–2118. ISSN: 0021-8812. https://doi.org/10.2527/jas2012-5738

PEARCE SC, Mani V, Boddicker RL, Johnson JS, Weber TE, Ross JW, Baumgard LH, and Gabler NK. 2012. Heat stress reduces barrier function and alters intestinal metabolism in growing pigs. Journal of Animal Science. 90(Suppl. 4):257–259. doi: https://dx.doi.org/10.2527/jas.52339.

PEARCE SC, Mani V, Weber TE, Rhoads RP, Patience JF, Baumgard LH, and Gabler NK. 2013a. Heat stress and reduced plane of nutrition decreases intestinal integrity and function in pigs. J. Anim. Sci. 91:5183–5193. ISSN: 0021-8812, https://doi.org/10.2527/jas2013-6759

PEARCE SC, Sanz Fernandez MV, Torrison J, Wilson ME, Baumgard LH, Gabler NK. 2015. Dietary organic zinc attenuates heat stress–induced changes in pig intestinal integrity and metabolism. Journal of Animal Science. 93(10):4702–4713. ISSN: 0021-8812. https://dx.doi.org/10.2527/jas2015-9018

PIEPER R, Vahjen W, Neumann K, Van Kessel AG and Zentek J, 2012. Dose-dependent effects of dietary zinc oxide on bacterial communities and metabolic profiles in the ileum of weaned pigs. ISSN:0931-2439. 96(5): 825−833. https://dx.doi.org/10.1111/j.1439-0396.2011.01231.x.

ROMO JM, Romo JA, Barajas R, Enríquez I, Silva G, Montero A. 2017. Efecto del consume de zinc orgánico en la respuesta productiva de la cerda y su camada. Abanico veterinario, Mayo-Agosto 2017; 7(2):43-59. ISSN 2448-6132. http://dx.doi.org/10.21929/abavet2017.72.4

SALES J. 2013. Effects of pharmacological concentrations of dietary zinc oxide on growth of post-weaning pigs: A meta-analysis. Biological Trace Element Research. 152 (3):343−349. ISSN: 0163-498. http://dx.doi.org/10.1007/s12011-013-9638-3

SANZ FMV, Johnson JS, Abuajamieh M, Stoakes SK, Seibert JT, Cox L, Kahl S, Elsasser TH, Ross JW, Isom SC., Rhoads RP, Baumgard LH. 2015. Effects of heat stress on carbohydrate and lipid metabolism in growing pigs. Physiological Reports. 3(2):e12315: 1-17. ISSN 2051-817X. http://dx.doi.org/10.14814/phy2.12315

SANZ FMV, Pearce SC, Gabler NK, Patience JF, Wilson ME, Socha MT, Torrison JL, Rhoads RP, and Baumgard LH. 2014. Effects of supplemental zinc amino acid complex on gut integrity in heat-stressed growing pigs. Animal. 8(1):43–50. ISSN: 1751-7311, http://dx.doi.org/10.1017/S1751731113001961

SLADE RD, Kyriazakis I, Carroll SM, Reynolds FH, Wellock IJ, Broom LJ and Miller HM, 2011. Effect of rearing environment and dietary zinc oxide on the response of group-housed weaned pigs to enterotoxigenic Escherichia coli O149 challenge. Animal. 5 (8): 1170–1178. ISSN: 1751-7311. http://dx.doi.org/10.1017/S1751731111000188

SONG ZH, Ke YL, Xiao K, Jiao LF, Hong QH, Hu CH. 2015. Diosmectite–zinc oxide composite improves intestinal barrier restoration and modulates TGF-β1, ERK1/2, and Akt in piglets after acetic acid challenge. Journal of Animal Science. 93:1599–1607. ISSN: 0021-8812. http://dx.doi.org/10.2527/JAS.2014-8580

STAR L, van der Klis JD, Rapp C, Ward TL. 2012. Bioavailability of organic and inorganic zinc sources in male broilers. Poultry Science. 91(12):3115-3120. ISSN: 0032-5791. https://doi.org/10.3382/ps.2012-02314

SUNDER GS, Panda AK, Gopinath NCS, Rama RSV, Raju MVLN, Reddy MR, and Kumar CV. 2008. Effects of higher levels of zinc supplementation on performance, mineral availability, and immune competence in broiler chickens. The Journal Applied Poultry Research. 17(1):79–86. ISSN: 1056-6171. https://doi.org/10.3382/japr.2007-00029

TERRIN G, Canani RB, Di Chiara M, Pietravalle A, Aleandri V, Conte F, De Curtis M. 2015. Zinc in Early Life: A Key Element in the Fetus and Preterm Neonate. Nutrients. 7(12):10427–10446. ISSN 2072-6643. http://dx.doi.org/doi:10.3390/nu7125542

WAEYTENS A, De Vos M, Laukens D. 2009. Evidence for a Potential Role of Metallothioneins in Inflammatory Bowel Diseases. Mediators of Inflammation. Article ID 729172: 9 pages. ISSN: 0962-9351. http://dx.doi.org/10.1155/2009/729172

WANG X, Valenzano MC, Mercado JM, Zurbach EP, Mullin JM. 2013. Zinc supplementation Modifies Tight Junctions and Alters Barrier Function of CACO-2 Human Intestinal Epithelial Layers. Digestive Diseases and Sciences. 58(1):77-87. ISSN: 0163-2116. http://dx.doi.org/10.1007/s10620-012-2328-8

YAN Y, Zhao Y, Wang H, and Fan M. 2006. Pathophysiological factors underlying heatstroke. Medical Hypotheses. 67(3):609–617. ISSN 0306-9877. https://doi.org/10.1016/j.mehy.2005.12.048

ZHANG B, Guo Y. 2009. Supplemental zinc reduced intestinal permeability by enhancing occludin and zonula occludens protein-1 (ZO-1) expression in weaning piglets. British Journal of Nutrition. 102:687–693. ISSN: 0007-1145. https://doi.org/10.1017/S0007114509289033

ZHONG W, McClain CJ, Cave M, Kang J and Zhou Z. 2010. The role of zinc deficiency in alchohol-induced intestinal barrier dysfunction. American Journal of Physiology, Gastrointestinal Liver Physiology. 298(5):G625-G633. ISSN: 0193-1857 https://dx.doi.org/10.1152/ajpgi.00350.2009


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