Heart Health and Long-Term Melatonin Use
Recent research indicates that individuals with insomnia who take melatonin supplements for over a year may face an increased risk of heart failure compared to those who do not use this common sleep aid.
Research Findings
The study showed a higher likelihood of diagnosis with heart failure, hospitalization due to the condition, or death from any cause among long-term melatonin users. These findings were presented at the American Heart Association’s Scientific Sessions 2025 in New Orleans.
Study Status and Limitations
This preliminary research has not yet been published in a peer-reviewed journal. Researchers emphasized that their data do not prove a direct cause-and-effect link between melatonin use and heart failure risks. Nevertheless, the findings raise important safety questions about prolonged melatonin use, suggesting the need for further investigation into its cardiovascular impacts.
Concerns About Melatonin Supplement Regulation
Melatonin supplements are frequently available over-the-counter without a prescription and lack regulatory oversight. This allows widespread use without medical supervision.
“Melatonin supplements may not be as harmless as commonly assumed.”
Author’s Summary
Long-term melatonin use may carry cardiovascular risks, highlighting the urgency for comprehensive research and better regulation of these widely accessible supplements.