Timberwolves vs. Knicks Prediction, Odds and Best NBA Prop Bets for Wednesday, Nov. 5

Timberwolves vs. Knicks Prediction, Odds and Best NBA Prop Bets for Wednesday, Nov. 5

Two NBA teams linked since a major trade before the 2024-25 season will meet for the first time in the 2025-26 season on Wednesday. The New York Knicks, led by Julius Randle, will host the Minnesota Timberwolves, featuring Karl-Anthony Towns.

The Timberwolves come off a Monday night victory against the Brooklyn Nets. Despite missing Anthony Edwards due to a hamstring injury, Minnesota has won two consecutive games and aims to return to the Western Conference Finals for the third straight season. Edwards is now listed as questionable for Wednesday's game.

The Knicks reached the Eastern Conference Finals last season and currently hold a 4-3 record for this season. They are on a four-game winning streak at home, recently defeating Chicago and Washington in consecutive games on Sunday and Monday. New York enters Wednesday's contest as the favorite on their home court.

Key Players and Storylines

Odds and Predictions

According to DraftKings Sportsbook, the Knicks are favored to win on their home floor. This matchup is highly anticipated as both teams are playoff contenders with strong recent performances.

"The Timberwolves have won two games in a row and are looking to get back to the Western Conference Finals for the third time in as many seasons."
"The Knicks are favored at home on Wednesday after winning four consecutive games on their court."

Author’s Summary

Wednesday's game promises a compelling showdown between two playoff-caliber teams, with the Knicks favored at home and the Timberwolves aiming to overcome injury challenges.

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Sports Illustrated Sports Illustrated — 2025-11-05